2016 Vol.22 No.1 PP 145-148

INFLAMMATORY CNVM BY TOXOPLASMOSIS: A REVIEW ARTICLE.

^*KENA JOSHI PUROHIT AND RENU DHASMANA.

Department of Opthalomology, S.R.H.U. Jolly Grant, DEHRADUN (UK) INDIA
*Corresponding Author Email : kena_166@yahoo.co.in

ABSTRACT

Choroidal neovascular membrane (CNVM) formation is a well-documented sight-threatening complication of posterior segment intraocular inflammation like Toxoplasmosis. Necrotizing retinochoroiditis caused by an obligate intracellular parasite, Toxoplasma gondii, is a common inflammatory lesion of the fundus accounting for up to 70 % of cases with retinochoroiditis . By virtue of high affinity for neural tissue and retinal ganglion cells , the T. gondii localizes in retina and causes recurring ocular inflammation. Focal necrotizing retinitis adjacent to old retinochoroidal scar is the characteristic lesion in ocular toxoplasmosis. The diagnosis of ocular toxoplasmosis can be made on the basis of clinical findings alone. Choroidal neovascularization (CNV) developing at the margins of the healed Toxoplasma scar lesion is an important cause of vision loss in young patients. The prevalence of choroidal neovascular membrane (CNVM) in toxoplasmosis cases is reported to be 2–19 % during the late stage of the disease . CNV has been well reported to occur during the stage of healed toxoplasmosis.

Key words : CNVM, Scar, Sight threatening, Toxoplasmosis.