2023 Vol. 29 No.1 PP 115-122

https://doi.org/10.33451/florafauna.v29i1pp115-122

Effect of coumestrol on the biochemical constituents of ovary and uterus of pups of Female albino rats

*Pragati Pathak and Mukesh Dixit¹

*Department of Zoology,
Govt. Model Science College, GWALIOR (MP) INDIA
¹Department of Zoology
Sarojni Naidu College, BHOPAL (MP) INDIA
*Corresponding Author : E-mail: pragatipathak2003@ gmail.com

ABSTRACT

In the current research, attempts were undertaken to evaluate the impact of coumestrol on some biochemical constituents of rats of F1 generation when these animals reached the ages of 2,4, and 6 months. The administration of coumestrol at different doses of 5,10 and 25 ug/kg during different days of pregnancy (Group-1 on the 10th and 13th day) and (Group-2 on the 15th and 18th day) caused a substantial rise in different parameters like the wet weight of uterus and ovary, protein contents, glycogen contents, the acid phosphatase, and alkaline phosphatase activity even at the age of 6 months.

KEY WORDS : Albino rats, Coumestrol phytoestrogens, Diethylstilbestrol