2024 Vol. 30 No.2 PP 317-324
https://doi.org/10.33451/florafauna.v30i2pp317-324
Harnessing the Antimicrobial Potential: A Comprehensive Review of Bacteriocin Production in Lactic Acid Bacteria
**Vijaya Gupta, Alka Ekka, Piyush Shukla and Ashok Shukla
1
1 *ICAR-Indian Institute of Sugarcane Research,
LUCKNOW (UP) INDIA 226 001
..
Department of Biotechnology,
Guru Ghasidas University, KONI-495009 BILASPUR (C.G.) INDIA
1HCW College, AMBIKAPUR-497001 (C.G.) INDIA
*Corresponding Author
E-mail : vijayagupta1982@gmail.com
ABSTRACT
Lactic acid bacteria (LAB) are the most studied bacterial genera with respect to bacteriocins, since some LAB strains
have a good potential for production by this kind of antimicrobial peptides. This review presents an extensive analysis of the
bacteriocin production system within LAB, focusing on — classification and specificity; biosynthesis machinery (including immunity);
action mechanisms against target microorganisms [antibacterial spectrum]; prospected applications in food preservation as well
as control/therapy treatments. This review highlights the genetic and environmental factors that influence bacteriocin production,
recent progress in optimization strategies as well hurdles and potential of using these natural antimicrobials to full extent. The
review also highlights the synergistic effects of bacteriocins with other antimicrobial compounds and their role in modulating gut
microbiota.
KEY WORDS : Antimicrobial peptides, Bacteriocins, Bioengineering, Food preservation, Lactic acid bacteria, Microbiome